Manufacturing

Capability

Manufacturing Capability

Servatus Ltd is an Australian-owned biopharmaceutical company
devoted to creating safe, effective, and reliable microbiome-based
therapeutic drugs to treat several chronic and debilitating
autoimmune diseases, as well as non-antibiotic treatments for
bacterial infections. For more information on this and our clinical trials
see: ‘our research’ page.

In addition to our innovative drug research and development, and
ongoing clinical trials, Servatus Ltd also owns a state-of-the-art
production facility.
Our own production facility means that Servatus are able to oversee
all aspects of the research development and production pipeline and
ensure that our live biotherapeutic drug candidates (LBPs) are made
to our high-standard and specifications, and removes the logistical
uncertainty often associated with outsourcing manufacturing.
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Completed Stage 1 Facility

Our Facility

Servatus Ltd has completed construction for stage 1 of our
State-of-the-art R&D manufacturing facility.
We have in-house capabilities such as fermenting, concentrating and drying our bacterial strains, all using our proprietary live biotherapeutic (LBP) production methodologies and custom designed automation skids used to seamlessly orchestrate our continuous manufacturing process.
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Completed Stage 2 Facility

Our Facilty

Stage two of the facility will ensure we are able to expand our manufacturing as well as our staff assets as the company grows, without continuously relocating.

Why does Servatus want to control all aspects of the LBP drug
development pipeline?


Manufacturing is a critical step in LBP development that is often
overlooked. Often the focus is directed on the research and initial
phases and not enough attention is directed to the physical and
logistical aspects of creating and producing a pharmaceutical product
en masse. This creates many technological issues and unnecessary
delays when scaling-up becomes a requirement. Servatus has
circumvented this by securing our own private manufacturing facility,
enabling us to test and scale-up production in-house, using our tried
and tested automated and continuous manufacturing process and
proprietary bioprocessing methods.

Controlling production at our facility and using our specially designed bioprocesses means we have been able to develop not only novel LBP
drug variants, but also we have developed our own proprietary media
and production systems, including very low temperature spray drying
for continuous production of high quality live microbial biotherapeutics.
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Our biomanufacturing process

Biomanufacturing process

Bio-manufacturing process using a proprietary closed system:
 Continuous production controlled by process automation skids using electrostatic spray drying (ESD) at low temperature which improves both recovery and production costs.

Our proprietary media has been developed for high viable cell density
(>1.0E10 cells/ml) and surpass the high standards of global regulatory compliance.

Contact Information

Contact Information